伴肾脏综合征出血热(HFRS)在世界大部分地区呈地方性流行。病源因子是汉坦病毒(Hantaan virus)。用间接免疫荧光抗体技术对采自全国各省所有年龄组人群的2000余份血清进行了本病病毒抗体的测定。血清阳性率的范围在0.3％至4.0％之间,全国平均阳性率是1.4％。大西洋地区的纽芬兰省(Newfoundland)和新伯伦瑞克省(New Brunswick)阳性率最高,高于朝鲜高度地方性流行区的阳性率。内陆省份的安大略省(Ontario),马尼托巴省(Manitoba)和阿尔伯达省(Alberta)抗汉坦病毒抗体的阳性率仅为 Hemorrhagic fever with kidney syndrome (HFRS) is endemic in most parts of the world. The etiological factor is Hantaan virus. Indirect immunofluorescence antibody was used to detect the antibody of the virus in more than 2000 sera collected from all age groups in all provinces in China. The seroprevalence ranged from 0.3% to 4.0% with a national average of 1.4%. Newfoundland and New Brunswick in the Atlantic Ocean had the highest positive rates, higher than the positive rates in North Korea’s highly endemic areas. The positive rates of anti-Hantaan virus antibodies in the inland provinces of Ontario, Manitoba and Alberta were only