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采用琼脂稀释法测定了５种抗菌剂对２０１株淋病奈瑟氏球菌的最低抑菌浓度（ＭＩＣ）。结果检出４株为产β－内酰胺酶菌株（ＰＰＮＧ），对青霉素和四环素的耐药率分别为５７．２％和８２．６％，其ＭＩＣ９０均已超过耐药界限（ＭＩＣ＝１μｇ／ｍｌ）。３５株耐环丙沙星，其中１５株同时对青霉素和四环素有耐药性。对大观霉素和头孢曲松的敏感性最高，分别为９９％和１００％，但检出２株耐大观霉素菌株，头孢曲松ＭＩＣ５０、ＭＩＣ９０明显高于国内外报道，应引起高度重视
The minimum inhibitory concentrations (MICs) of 5 antibacterial agents against 201 strains of Neisseria gonorrhoeae were determined by agar dilution method. Results Four isolates were identified as PPNG. The resistance rates to penicillin and tetracycline were 57.2% and 82.6%, respectively, and their MIC90 were beyond the resistance limit (MIC = 1μg / ml). 35 resistant to ciprofloxacin, of which 15 were simultaneously resistant to penicillin and tetracycline. The sensitivity to spectinomycin and ceftriaxone was the highest (99% and 100%, respectively). However, two strains of spectinomycin resistant to penicillin were detected. The MIC50 and MIC90 of ceftriaxone were significantly higher than those reported at home and abroad, which should be paid great attention