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目的比较不同方法终止14～16周妊娠的效果,探讨更为安全、简便的引产方法。方法选择自愿要求终止妊娠且符合计划生育政策的孕14～16周孕妇80例,随机分成二组。A组应用米非司酮配伍米索前列醇法。B组行依沙吖啶100mg羊膜腔内注射引产法。观察二组引产成功率、宫缩发动时间、总产程时间、产后出血量、软产道损伤等情况。结果二组在软产道损伤、产后出血方面比较,差异无统计学意义(P>0.05)。A组引产成功率优于B组(P<0.05),宫缩发动时间、总产程时间等方面明显优于B组(P<0.01)。结论米非司酮配伍米索前列醇用于终止14～16周妊娠是安全有效的。其操作较为简便,并且产程较传统的依沙吖啶羊膜腔内注射引产法缩短,且成功率高。
Objective To compare the effect of different methods on the termination of pregnancy in 14 ~ 16 weeks to explore more safe and easy induction of labor. Methods Eighty pregnant women, aged 14 to 16 weeks who voluntarily requested termination of pregnancy and who were in line with family planning policy, were randomly divided into two groups. A group of mifepristone with misoprostol method. Group B, according to acridine 100mg amniotic intraception by induction of labor. Observe the success rate of two groups of induced labor, uterine contraction time, total labor time, postpartum hemorrhage, soft birth canal injury and so on. Results There was no significant difference between the two groups in terms of soft birth canal injury and postpartum hemorrhage (P> 0.05). The success rate of induction of labor in group A was better than that of group B (P <0.05), the time of uterine contractions and the duration of labor were significantly better than those in group B (P <0.01). Conclusion The combination of mifepristone and misoprostol is effective and safe for terminating 14-16 weeks gestation. Its operation is relatively simple, and the labor process than the traditional acridine acridine intramuscular injection of induction of labor shortening, and a high success rate.