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目的探讨脑肿瘤并发脑疝的临床特点及诊疗策略。方法对2例儿童脑肿瘤并发脑疝的临床资料进行回顾分析,结合文献复习探讨。结果例1急性起病,以发热、头痛、昏迷为主要表现,头颅CT示左侧小脑占位性病变,行手术治疗,术后予药物控制颅内高压,疗效欠佳。家属放弃救治,患儿死亡。例2慢性病程,以头晕、头痛、走路不稳为早期表现,头颅MR示桥脑异常信号,考虑胶质瘤,予化疗及中药治疗,疗效欠佳,晚期出现昏迷,复查头部CT示脑坏死、脑积水、脑疝。家属坚持救治,患儿持续昏迷。2例患儿颅内高压控制不佳致脑坏死,治疗费用巨大。结论脑肿瘤并发脑疝死亡风险高,控制颅内高压、维持有效脑灌注压可改善预后。倡议我国对脑死亡立法,对脑坏死患者合理配置医疗资源。
Objective To investigate the clinical features and diagnosis and treatment strategies of brain tumors complicated by brain herniation. Methods The clinical data of 2 children with brain tumor complicated with cerebral hernia were retrospectively analyzed and reviewed. The results of an acute onset of cases, with fever, headache, coma as the main performance of the cranial CT showed left cerebellar space-occupying lesions, surgery, postoperative medication to control intracranial hypertension, poor efficacy. Family members to give up treatment, children died. Example 2 chronic disease, dizziness, headache, walking instability as an early manifestation of cranial MR abnormal brain signal, consider glioma, chemotherapy and traditional Chinese medicine treatment, poor efficacy, late coma, review head CT brain Necrosis, hydrocephalus, hernia. Family members persist in treatment, children continue to coma. 2 cases of poor control of intracranial hypertension caused brain necrosis, treatment costs huge. Conclusion Brain tumor complicated with cerebral hernia is associated with a high risk of death, controlling intracranial hypertension and maintaining effective cerebral perfusion pressure may improve prognosis. It is suggested that China should legislate on brain death and rationally allocate medical resources to patients with brain-dead disease.