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目的:观察飞秒激光小切口角膜基质透镜取出术(SIMLE)的并发症。方法:回顾性研究。分析长春爱尔眼科医院2016年5月至2019年5月近视768例(1 500眼)行SMILE矫正的临床资料，观察其并发症。结果:术后并发症共21眼(1.40%)，其中弥漫性板层角膜炎3眼(0.20%)，角膜基质层间雾状浑浊4眼(0.27%)，感染1眼(0.07%)，欠矫3眼(0.20%)，过矫3眼(0.20%)，屈光回退2眼(0.13%)，切口处上皮植入1眼(0.07%)，角膜帽下异物2眼(0.13%)，角膜板层层间微皱褶2眼(0.13%)。结论:SMILE并发症较少，手术安全性、稳定性较好。“,”Objective:To observe the complications of femtosecond laser small incision lenticule extraction (SMILE).Methods:This was a retrospective study. The clinical data of 1 500 eyes of 768 cases of myopia who underwent SMILE from May 2015 to May 2019 in Changchun Aier Eye Hospital were analyzed. The operative complications were observed.Results:The operative complications occurred in 21 eyes (1.40%), including diffuse lamellar keratitis in 3 eyes (0.20%), corneal stromal haze in 4 eyes (0.27%), infection in 1 eye (0.07%), under correction and over correction both in 3 eyes (0.20%), refractive regression in 2 eyes (0.13%), epithelial implantation in the incision in 1 eye (0.07%), foreign body under the corneal cap in 2 eyes (0.13%), and lamellar microfold in 2 eyes (0.13%).Conclusion:There are few complications of SMILE, and the operation is safe and stable.