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目的:比较出口梗阻型便秘(OOC)与非OOC患者的高分辨率肛门直肠测压结果，探讨肛门直肠动力异常和直肠感觉功能障碍在OOC发病中的作用。方法:回顾性分析2018年1月至2019年7月于首都医科大学附属北京同仁医院消化内科就诊的103例功能性便秘患者的高分辨率肛门直肠测压检查结果，根据诊断标准将其分为OOC组(56例)和非OOC组(47例)。比较OOC组与非OOC组患者的一般资料(年龄、性别构成)，以及肛门直肠动力(肛管静息压、肛门括约肌长度、肛管最大收缩压、肛管持续收缩时间、肛门残余压和直肠排便压)和直肠感觉功能(初始感觉阈值、初始排便阈值和最大耐受阈值)指标。统计学方法采用配对n t检验和卡方检验。n 结果:OOC组患者的年龄与非OOC组比较[(63.5±14.2)岁比(61.6±13.4)岁]，差异无统计学意义(n P>0.05)；OOC组的男性比例高于非OOC组[41.1%(23/56)比23.4%(11/47)]，差异有统计学意义(n χ2＝-3.607，n P0.05)；OOC组患者的排便时肛门残余压和直肠排便压均高于非OOC组[(67.00±21.13) mmHg比(51.43±0.74) mmHg、(51.52±23.70) mmHg比(36.49±12.55) mmHg]，差异均有统计学意义(n t＝-3.734、-3.909，n P均0.05). The proportion of male of OOC group was higher than that of non-OOC group (41.1%, 23/56 vs. 23.4%, 11/47), and the difference was statistically significant (n χ2=-3.607, n P0.05). The residual anal pressure and rectal defecation pressure of OOC group were both higher than those of non-OOC group ((67.00±21.13) mmHg vs. (51.43±0.74) mmHg; (51.52±23.70) mmHg vs. (36.49±12.55) mmHg), and the differences were statistically significant (n t=-3.734 and -3.909, both n P<0.01). The proportion of patients with rectal sensation of OOC group and non-OOC group was 46.4%(26/56) and 51.1%(24/47), respectively.n Conclusions:Abnormalities of anorectal motility and rectal sensation are common in OCC patients, and insufficient anal relaxation during defecation may be an important pathogenic factor of OCC.