肿瘤是基因发生变化的疾病，是累积性基因损伤在转化表型方面达到顶点的结果。在有关肿瘤基因治疗方面，将“自杀基因”（ｓｕｉｃｉｄｅｇｅｎｅ）导入肿瘤细胞，而将无毒性前体药物在肿瘤细胞内代谢为毒性产物，进而杀伤肿瘤细胞的“自杀基因”疗法占有重要地位并显示出良好 Cancer is a genetically altered disease and is the result of cumulative genetic damage reaching the culmination of transformed phenotypes. In relation to tumor gene therapy, “suicide gene” is introduced into tumor cells, and non-toxic prodrugs are metabolized into toxic products in tumor cells, thereby killing tumor cells. “Suicide gene” therapy occupies an important position and displays Good