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目的了解2008年云南省昌宁县食品、公共场所从业人员乙肝病毒(HBV)感染情况,确定管理的重点人群。方法采用酶联免疫吸附试验(ELISA法)对2008年共3473例从业人员进行HBsAg检测,阳性血清进一步检测HBsAg、HBsAb(表面抗体)、HBeAg(e抗原)、HBeAb(e抗体)、HBcAb(核心抗体),即乙肝血清标志物5项指标检测,并对结果进行分析。结果2008年从业人员HBsAg阳性率为0.89%,男女差异无统计学意义(χ2=0.03,P>0.05),在食品、公共场所从业人员中构成比以前者高,但两者之间差异无统计学意义(χ2=0.18,P>0.05)。年龄分布以40岁年龄组最高,HBsAg阳性血清经5项指标检测HBsAg+HBeAb+HBcAb模式占38.71%,HBsAg+HBeAg+HBcAb模式占25.81%,HBsAg+HBcAb模式占35.48%。结论食品、公共场所行业人员进行一年一次预防性健康检查和上岗前预防性健康检查,是降低HBV感染率的有效干预措施。
Objective To understand the status of hepatitis B virus (HBV) infection among food and public places practitioners in Changning County, Yunnan Province in 2008 and to identify the key population for management. Methods ELISA was used to detect HBsAg in 3473 workers in 2008. The positive serum samples were further tested for HBsAg, HBsAb, HBeAg, HBeAb, HBcAb (core Antibody), that is, hepatitis B serum markers 5 indicators detection, and the results were analyzed. Results The positive rate of HBsAg in 2008 was 0.89%. There was no significant difference between male and female (χ2 = 0.03, P> 0.05). The proportion of HBsAg among the employees in food and public places was higher than the former, but the difference was not statistically Significance (χ2 = 0.18, P> 0.05). The distribution of HBsAg + HBeAb + HBcAb accounted for 38.71%, HBsAg + HBeAg + HBcAb accounted for 25.81%, HBsAg + HBcAb accounted for 35.48%. Conclusions The annual preventive health examination and pre-employment preventive health check-ups conducted by food and public places workers are effective interventions to reduce the HBV infection rate.