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目的:探讨解毒益气活血方对体外血管形成的抑制作用。方法:采用MTT法观察解毒益气活血方对人脐静脉内皮细胞(HUVECs)增殖的影响。结果:解毒益气活血方在10%~20%浓度范围内,具有抑制血管内皮增殖作用(内皮存活率在63.8%~58.5%),且均与对照组有显著差异。结论:解毒益气活血方(10%~20%)在体外具有抑制血管增殖作用。
Objective: To investigate the inhibitory effect of Jiedu Yiqi Huoxue Recipe on angiogenesis in vitro. Methods: The effects of Jiedu Yiqi Huoxue Recipe on the proliferation of human umbilical vein endothelial cells (HUVECs) were observed by MTT assay. Results: Jiedu Yiqi Huoxue Fang inhibited the proliferation of vascular endothelial cells (endothelial viability at 63.8% -58.5%) within the concentration range of 10% -20%, and both were significantly different from the control group. Conclusion: Jiedu Yiqi Huoxue Fang (10% ~ 20%) has the effect of inhibiting the proliferation of blood vessels in vitro.