肿瘤坏死因子-α(TNF-α)是存在于炎症局部的主要细胞因子。它通过启动凋亡机制引起细胞死亡。某些种类的细胞有很强的抗凋亡的能力。TNF-α在激活的同时也刺激了核因子-кB(NF-кB)的生成。NF-кB最常见的形式是一个由50kD的蛋白质亚基(P50)和一个65kD的蛋白质亚基(P65或RelA)组成的异二聚体。作者发现,转录因子NF-кB在淋巴 Tumor necrosis factor-α (TNF-α) is a major cytokine present in the local area of ​​inflammation. It causes cell death by initiating apoptosis mechanisms. Some kinds of cells have a strong anti-apoptotic ability. TNF-alpha stimulates the production of nuclear factor-kappa B (NF-кB) while being activated. The most common form of NF-кB is a heterodimer consisting of a 50 kD protein subunit (P50) and a 65 kD protein subunit (P65 or RelA). The authors found that the transcription factor NF-кB is in the lymphatics