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目的:了解不同年龄段儿童鼻病毒的检测结果及临床表现。方法:采集2019年1—12月汕头大学医学院第二附属医院住院的2 908例呼吸道感染患儿的咽拭子,应用多重PCR和Luminex悬浮液态芯片技术进行呼吸道病原体核酸检测,对单一鼻病毒阳性的病例分年龄段进行分析,比较其检测结果、临床症状、影像学及实验室检查指标特点。结果:单一鼻病毒阳性170例(5.85%,170/2 908),不同年龄组间阳性率比较差异有统计学意义(n χ2=9.66,n P28日龄~1岁组阳性率最高(7.80%),>1~3岁组阳性率最低(4.50%)。不同年龄组间均可出现发热、咳嗽、喘息表现,分别以>6岁、>28日龄~1岁和>1~3岁组比例最高(n χ2=12.82、21.78、12.54,n P均6岁年龄组比例最高(50.00%)。影像学显示3岁以下年龄组主要表现为支气管肺炎。不同年龄组间淋巴细胞计数升高和降低比例差异有统计学意义(n χ2=31.41,29.90,n P均1-3 years old group (4.50%) . Symptoms of fever, cough and wheezing could occur in different age groups with the highest proportions in >6, >28 days-1 year old and >1-3 years old groups, respectively (n χn 2=12.82, 21.78 and 12.54, n P all6 years old group (50.00%) . The chest X-ray results showed that bronchopneumonia was common in children under 3 years old. The proportions of increased and decreased lymphocyte count were significantly different in different age groups (n χn 2=31.41 and 29.90, n P both<0.05) .n Conclusions:The detection rate of rhinovirus is the highest in infancy. The main symptoms of infected newborns are shortness of breath and cyanosis, and the chest X-ray usually shows bronchopneumonia. The main symptoms of infected infants are cough and wheezing. In school-aged children, the main symptoms are fever and headache, and the results of chest X-ray are usually normal.