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目的:探讨短期持续胰岛素皮下脉冲式注射治疗(胰岛素泵强化治疗CSII)初诊2型糖尿病(T2DM)血糖控制的影响。方法:对60例空腹血糖>10mmol/L的初诊T2DM患者,分别用持续胰岛素皮下注射治疗(CSII)组32例和多次胰岛素皮下注射治疗(MSII)组28例,分析比较两组治疗前后血糖控制效果、胰岛素用量及血糖控制达标时间。结果:两组血糖均显著下降(P<0.01);血糖达标胰岛素日最大用量:CSII组(0.89±0.35)U/(kg·d)较MSII组(1.08±0.31)U/(kg·d)明显减少,差异有显著性;平均控制天数:CSII组(6.3±2.1)天,较MSII组(9.5±4.9)天明显减少,差异有显著性。结论:CSII方式较MSII方式更快速有效控制血糖。
Objective: To investigate the effect of short-term continuous insulin subcutaneous pulse injection (insulin pump intensive treatment of CSII) on newly diagnosed type 2 diabetes (T2DM) blood glucose control. Methods: Totally 32 newly diagnosed T2DM patients with fasting plasma glucose> 10mmol / L were treated with continuous insulin subcutaneous injection (CSII) and 28 with multiple subcutaneous injection of insulin (MSII) respectively. The levels of blood glucose Control effect, insulin dosage and blood glucose control standard time. Results: The blood glucose of the two groups were significantly decreased (P <0.01). The maximum daily dose of insulin in the blood glucose level was (0.89 ± 0.35) U / (kg · d) in CSII group compared with 1.08 ± 0.31 U / (kg · d) The average number of control days was significantly lower in CSII group (6.3 ± 2.1 days) than that in MSII group (9.5 ± 4.9) days, the difference was statistically significant. CONCLUSIONS: The CSII approach controls blood glucose faster and more effectively than the MSII approach.