慢性乙型病毒性肝炎是疾病负担较重的一种疾病,在各型病毒性肝炎中对人类健康危害最为严重。目前乙型肝炎病毒的慢性感染状态缺乏有效根治措施,患者预后与很多因素有关,如病毒载量、甲状腺激素水平、甲胎蛋白含量、肝硬化失代偿、凝血酶原时间等。研究局限于单因素分析,多因素综合分析文章较少。国外较频繁报道患者自我评价健康的生存质量评价量表,如MOSSF-36量表、CLDQ问卷,并广泛应用于评价患者的功能状态和健康相关生存质量。但国内用以对慢性乙肝生存质量评价不多见。 Chronic hepatitis B is a disease with a heavier burden of disease and harms human health in all types of viral hepatitis. Currently, chronic hepatitis B virus infection lacks effective curative measures. The prognosis of patients is related to many factors such as viral load, thyroid hormone level, alpha-fetoprotein content, decompensation of liver cirrhosis, and prothrombin time. Research limited to univariate analysis, multi-factor comprehensive analysis of articles less. Frequently reported foreign countries to self-evaluation of patients with a healthy quality of life evaluation scale, such as MOSSF-36 scale, CLDQ questionnaire, and is widely used to evaluate the patient’s functional status and health-related quality of life. However, the domestic use of chronic hepatitis B quality of life is rare.