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报道了经口给予四种温里方剂以及单味附子对腹腔注射内毒素引起大鼠内毒素休克的预防作用。 材料与方法:以生理盐水溶解内毒素(0111: B4;E.coli脂多糖),浓度为3mg/ml,腹腔注射(ip)。组成汉方方剂的五种生药分别为甘草、干姜、附子(经高温高压制成粉末以降低毒性)、人参与茯苓。四种方刊分别为甘草干姜汤(KK)、四逆汤(SG)、四逆加人参汤(SN)与茯苓四逆汤(BS)。以热水提取,经低温真空干燥制备提取物。用前以蒸馏水溶解制备成适当浓度灌胃给药。动物所用剂量为
It was reported that the oral administration of four kinds of Wenli formula and single flavored aconite to prevent intraperitoneal injection of endotoxin induced endotoxin shock in rats. Materials and Methods: The endotoxin (0111: B4; E.coli lipopolysaccharide) was dissolved in physiological saline at a concentration of 3 mg/ml and injected intraperitoneally (ip). The five crude herbs that make up the Chinese herbal formula are licorice, dried ginger, aconite (made of powder under high temperature and high pressure to reduce toxicity), and people involved in wolfberry. The four kinds of prescriptions were licorice gancao decoction (KK), Sini decoction (SG), Sinijiao ginseng decoction (SN) and Fusi Sini decoction (BS). Extracted with hot water and dried at low temperature to prepare extracts. Dissolved in distilled water before use to prepare appropriate concentrations of intragastric administration. The dose used by the animal is