归巢受体是一类位于淋巴细胞表面的粘附分子,通过与其配体的结合选择性地使淋巴细胞向特定组织部位归巢,不仅在淋巴细胞发育、活化和机体免疫防御反应中发挥重要作用,而且可以促进恶性淋巴瘤细胞的生长,提高肿瘤侵袭能力,广泛参与恶性淋巴瘤的播散过程,并与临床预后相关。 Homing receptors are a class of adhesion molecules located on the surface of lymphocytes that selectively target lymphocytes to specific tissue sites by binding to their ligands and play an important role not only in lymphocyte development, activation, and immune defense response But also promote the growth of malignant lymphoma cells and improve the ability of tumor invasion. It is widely involved in the dissemination of malignant lymphoma and is associated with clinical prognosis.