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人乳头瘤病毒(HPV)在女性人群中感染率较高,与子宫颈癌及癌前病变关系密切。目前公认HPV是引起上述病变的主要致病因素。子宫颈癌是一种常见妇科恶性肿瘤,其发病率逐年上升,全世界每年约有四十七万新发病例,并导致23万人死亡。随着分子生物学与流行病学的发展,对HPV的检测和治疗成为预防子宫颈癌的重要手段。HPV疫苗研究及临床应用也进入崭新的时代。对HPV与子宫颈癌相关性的研究进展综述。
Human papillomavirus (HPV) has a high infection rate in female population, which is closely related to cervical cancer and precancerous lesions. HPV is currently recognized as the main cause of these lesions. Cervical cancer is a common gynecological malignant tumor whose incidence is increasing year by year, with about 470,000 new cases occurring each year in the world and causing 230,000 deaths. With the development of molecular biology and epidemiology, the detection and treatment of HPV become an important means to prevent cervical cancer. HPV vaccine research and clinical applications have also entered a new era. Research progress on the correlation between HPV and cervical cancer.