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目的通过B超检查糖尿病神经源性膀胱患者残余尿量和患者临床症状来评价甲钴胺联合甲氧氯普胺治疗糖尿病神经源性膀胱的疗效。方法选择糖尿病神经源性膀胱患者104例随机分为2组,对照组仅给予基础治疗,治疗组为基础治疗+甲钴胺+甲氧氯普胺。结果治疗后治疗组患者膀胱残余尿量减少量为(103±36)mL,对照组膀胱残余尿量减少量为(68±21)mL,差异有统计学意义(P<0.05)。临床症状治疗组也明显好于对照组,差异有统计学意义。结论甲钴胺联合甲氧氯普胺治疗糖尿病神经源性膀胱效果显著。
Objective To evaluate the efficacy of mecobalamin and metoclopramide in the treatment of diabetic neurogenic bladder by ultrasonography of residual urine volume in patients with neurogenic bladder and clinical symptoms. Methods A total of 104 patients with diabetic neurogenic bladder were randomly divided into 2 groups. The control group received only basic treatment. The treatment group was treated with mecobalamin and metoclopramide. Results The decrease of bladder residual urine volume was (103 ± 36) mL in the treatment group and (68 ± 21) mL in the control group, the difference was statistically significant (P <0.05). Clinical symptoms were also significantly better than the control group, the difference was statistically significant. Conclusion Mecobalamin combined with metoclopramide treatment of diabetic neurogenic bladder effect was significant.