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特发性血小板减少性紫癜病(ITP)是血小板减少所致的后天性出血性疾病。小儿期发病多数呈急性自限的一过性病程。但是,一部分所谓慢性型的抗药性病例,临床上成了难题。肾上腺皮质类固醇(简称类固醇)疗法虽然可以长期应用,但有时无效或有副作用,且有效病例约半数随着药物减量血小板数再度减少,治疗率仅达24%。作者从1974年6月到1987年3月收治ITP患者42例,其中诊断为慢性型8例,采用类固醇疗法(去氢氢化考的松1～2 mg/kg/d),其中4例从用药后第4天起到第8天,血小板数达正常范围,以后全部病例又继续减少。首次用类固醇缓解的2例及对类固
Idiopathic thrombocytopenic purpura (ITP) is an acquired hemorrhagic disease caused by thrombocytopenia. The majority of pediatric onset of acute self-limiting transient course. However, some of the so-called chronic drug-resistant cases have become clinically problematic. Adrenal corticosteroids can be long-term use, but sometimes ineffective or have side effects, and about half of the effective cases with the reduction of drug reduction in platelet number again, the treatment rate of only 24%. Forty-two patients with ITP were enrolled from June 1974 to March 1987, of whom 8 were diagnosed as having chronic form of steroid therapy (1 to 2 mg / kg / day of hydrocortisone), of which 4 were treated with medication After the first 4 days to play the first 8 days, platelets up to the normal range, after all cases continue to decrease. The first two cases of steroid relief and the type of solid