哌甲酯(利他林、Methylphenidate)是世界各国目前用以治疗脑功能轻微失调(MBD)的首选药物。我们在1978年10月至1980年7月曾用此药治疗MBD241例,取得较好效果。现摘要报道如下: 全组241例,男184例,女57例。关于MBD的临床表现、诊断标准和治疗方法请参阅本期15页“苯丙胺治疗脑功能轻微失调1,329例”一文(哌甲酯起始剂量为5毫克)。治疗结果如下:241例中有效者223名,占92.53％。其中158例系原来应用苯丙胺治疗的病例:34例因苯丙胺耐药而改用哌甲酯,结果31例(91.17％)有效;71例因 Methylphenidate (Methylphenidate) is the drug of choice in countries around the world for the treatment of mild dysfunction (MBD). We in October 1978 to July 1980 had this drug treatment of MBD 241 cases, achieved good results. The summary is reported as follows: The whole group of 241 cases, 184 males and 57 females. For the clinical manifestations, diagnostic criteria and treatment of MBD, please refer to the 15th issue of this issue, “1,329 cases of mild dysfunction of amphetamines” (methylphenidate starting dose 5 mg). The treatment results are as follows: 223 of the effective in 223 cases, accounting for 92.53%. 158 of them were treated with amphetamine: 34 cases were switched to methylphenidate because of amphetamine resistance, 31 cases (91.17%) were effective; 71 cases were due to