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采用两种单克隆抗体IRMA,联合测定26例胰腺癌,21例良性胰胆疾病和20例非胰腺消化道肿瘤血清CA242和CA19—9的水平。结果示胰腺癌组二种肿瘤相关抗原血清水平及阳性率明显高于其他两组,联合检测的敏感性和准确性优于单独抗原检测,对胰腺癌的诊断有较高的临床价值。
Two monoclonal antibodies, IRMA, were used for the combined determination of serum CA242 and CA19-9 levels in 26 pancreatic cancers, 21 benign pancreatobiliary diseases and 20 non-pancreatic digestive tract tumors. The results showed that the serum levels and positive rates of the two types of tumor-associated antigens in the pancreatic cancer group were significantly higher than those in the other two groups. The sensitivity and accuracy of the combined detection were better than that of the antigen alone, and had a higher clinical value in the diagnosis of pancreatic cancer.