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目的:了解恩施州药品不良反应(ADR)报告中的不合理用药比例、形式、涉及的主要药物品种等。方法:用Excel对1998～2008年恩施州ADR监测中心收集的ADR病例进行了统计、分析,重点分析不合理用药典型病例。结果:不合理用药在ADR报告中占32.1%,主要为预防用抗菌药不合理、超适应证用药、超剂量用药、疗程过长、重复用药、配伍禁忌等;涉及品种主要为抗菌药物、中药、心脑血管系统用药。结论:该地区ADR报告中存在较突出的不合理用药情况,折射出我国部分地区在合理用药方面存在一定问题,应引起高度重视和监管。
OBJECTIVE: To understand the proportion and form of unreasonable drug use in Enshi state drug adverse reaction (ADR) report and the main drug species involved. Methods: The ADR cases collected by the ADR monitoring center in Enshi Prefecture from 1998 to 2008 were statistically analyzed with Excel, and the typical cases of irrational drug use were analyzed emphatically. Results: The unreasonable use of drugs accounted for 32.1% of the ADR reports, mainly for the prevention of unreasonable use of antimicrobial agents, hyper-indications, overdosage, overdose, repeated use of drugs, incompatibility and other incompatibilities; , Cardiovascular and cerebrovascular system medication. Conclusion: There are prominent cases of unreasonable drug use in the ADR report in the region, which reflects that there are some problems in the rational use of drugs in some areas of our country and should be given high priority and supervision.