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钨及其合金的主要成分包括钨、钴和碳化钨,是制造硬质合金的主要原料。本文介绍了钨及其合金的接触水平及主要健康影响,总结了钨及其合金的剂量反应关系和遗传易感性研究结果,认为钨及其合金的外接触剂量与内接触剂量(如尿、血等生物样本)或某些生物标志存在一定的相关性,但其健康影响具有一定的个体差异。在我国进行钨及其合金的健康影响评估研究,是防治新增法定职业病——硬金属肺病的迫切需求。
The main components of tungsten and its alloys include tungsten, cobalt and tungsten carbide, which are the main raw materials for the manufacture of cemented carbides. This article describes the contact level of tungsten and its alloys and their main health effects. The dose-response relationship and genetic susceptibility of tungsten and its alloys are summarized. It is concluded that the external and internal contact doses of tungsten and its alloys (such as urine and blood And other biological samples) or some biomarkers have some relevance, but their health effects have some individual differences. The research on the health impact assessment of tungsten and its alloys in our country is an urgent need to prevent and control the new statutory occupational disease - hard metal lung disease.