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目的观察磷酸肌酸钠治疗新生儿缺氧缺血性心肌损害疗效。方法选择2013年1月至2015年12月因缺氧缺血性心肌损害而住院的新生儿100例。将患儿随机分成2组,一组采用常规治疗作为对照组,一组采用磷酸肌酸钠治疗作为治疗组,两组均为50例。两组采取不同的治疗措施,常规方法和磷酸肌酸钠治疗方法,对比两组的治疗效果。结果两组疗效差异较为明显。治疗组总有效率为84.0%,对照组总有效率68.0%,两组数据比较具有统计学意义(x2=4.39,P<0.05)。同时对于心电图、心肌酶谱等重要的反应心肌损害程度的体征参数,治疗组较对照组的恢复速度快,其恢复到正常水平的比例也比对照组高,两组数据比较具有统计学意义(x2=4.14,P<0.05)。结论磷酸肌酸钠能有效治疗缺氧缺血性心肌损害。
Objective To observe the therapeutic effect of sodium creatine phosphate on neonatal hypoxic-ischemic myocardial damage. Methods 100 newborns hospitalized for hypoxic-ischemic myocardial damage from January 2013 to December 2015 were selected. The children were randomly divided into two groups, one group treated with conventional therapy as a control group, one group treated with sodium creatine phosphate as a treatment group, both groups were 50 cases. The two groups took different treatment measures, routine methods and sodium phosphate creatine treatment, compared the two groups of treatment. Results The difference between the two groups is more obvious. The total effective rate was 84.0% in the treatment group and 68.0% in the control group. The data of two groups were statistically significant (x2 = 4.39, P <0.05). At the same time for ECG, myocardial enzymes and other important indicators of the degree of myocardial damage response parameters, the recovery rate of the treatment group compared with the control group fast recovery to normal levels than the control group, the two groups of data was statistically significant ( x2 = 4.14, P <0.05). Conclusion Sodium creatine phosphate can effectively treat hypoxic-ischemic myocardial damage.