论文部分内容阅读
纤维连接蛋白(Fn)是一种广泛分布于体液和细胞外基质的高分子糖蛋白,是一个免疫调理素,参与细胞免疫过程。在移植肾急性排斥时肾小球组织内Fn含量增加,提示Fn参与肾排斥过程。我们通过对肾移植患者血浆Fn浓度的动态监测,观察在排斥反应、急性肾小管坏死(ATN)和并发感染时的血浆Fn演变规律,以期探讨动态监测血浆Fn浓度能否对这些并发症作出早期预测和鉴别诊断价值。 一、材料和方法 1.实验对象:肾移植随访患者39例,肾移植术后
Fibronectin (Fn) is a macromolecular glycoprotein widely distributed in the body fluids and extracellular matrix. It is an immunomodulatory hormone involved in cellular immune processes. In acute rejection of renal grafts, the content of Fn in glomerular tissue increased, suggesting that Fn is involved in renal rejection. Through the dynamic monitoring of plasma Fn concentrations in renal transplant recipients, we observed the evolution of plasma Fn during rejection, acute tubular necrosis (ATN) and concurrent infection in order to investigate whether the dynamic monitoring of plasma Fn concentration can early respond to these complications Predict and differentiate diagnostic value. First, materials and methods 1. Subjects: 39 cases of renal transplantation follow-up, after renal transplantation