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目的探讨老年心力衰竭(以下简称心衰)患者血清NT-proBNP水平、APACHEⅡ评分与预后的相关性。方法测定97例ICU心衰患者血清NT-proBNP水平和进行急性生理学及慢性健康状况评分(APACHEⅡ评分)。以APACHEⅡ评分10分和20分为界分为3个组别。比较各组与NT-proBNP水平的关系。另外将生存组和死亡组分别作血清NT-proBNP水平及APACHEⅡ评分比较。结果 APACHEⅡ评分21～30组血清NT-proBNP水平明显高于11～20分组(P<0.05),APACHEⅡ评分>30分组动脉血清NT-proBNP水平明显高于>20分组(P<0.05)。NT-proBNP水平与APACHEⅡ评分相关,死亡组NT-proBNP水平明显高于存活组。结论血NT-proBNP检测方便、快捷与APACHEⅡ评分结合,可更客观反映老年心衰患者的预后。
Objective To investigate the correlation between serum NT-proBNP level, APACHEⅡ score and prognosis in elderly patients with heart failure (HF). Methods Serum NT-proBNP levels were measured in 97 ICU patients with heart failure and acute physiology and chronic health status score (APACHEⅡ). APACHE Ⅱ score of 10 points and 20 points divided into three groups. The relationship between each group and NT-proBNP level was compared. In addition, the survival group and death group were compared for serum NT-proBNP level and APACHE II score. Results Serum levels of NT-proBNP in APACHEⅡscore 21-30 group were significantly higher than those in 11-20 group (P <0.05). Serum NT-proBNP levels of APACHEⅡ score> 30 group were significantly higher than those in> 20 group (P <0.05). The level of NT-proBNP was related to APACHEⅡscore, and the level of NT-proBNP in death group was significantly higher than that in survivors. Conclusion The detection of blood NT-proBNP is convenient and quick combined with APACHEⅡscore, which can objectively reflect the prognosis of elderly patients with heart failure.