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目的探讨替吉奥胶囊联合草酸铂治疗晚期胃癌的临床效果。方法 126例晚期胃癌患者按照住院先后顺序分为研究组与对照组,每组63例。给予对照组患者多西他赛联合草酸铂治疗,给予研究组患者替吉奥胶囊联合草酸铂治疗。对比两组患者的近期效果。结果研究组患者治疗有效率为63.5%,明显高于对照组的28.6%,差异有统计学意义(P<0.05);研究组患者临床受益率为88.9%,明显高于对照组的57.1%,差异有统计学意义(P<0.05);研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论替吉奥胶囊联合草酸铂治疗晚期胃癌有较好的近期效果,且不良反应轻,安全性高,值得进行深入研究和推广。
Objective To investigate the clinical effect of tigeo capsule combined with oxaliplatin in the treatment of advanced gastric cancer. Methods 126 cases of advanced gastric cancer patients were divided into study group and control group according to the order of hospitalization, each group of 63 cases. Docetaxel plus oxaliplatin was given to patients in the control group, and patients in the study group were treated with oxaliplatin in combination with GEO capsules. Compare the immediate effect of two groups of patients. Results The effective rate of treatment in study group was 63.5%, which was significantly higher than that in control group (28.6%, P <0.05). The clinical benefit rate in study group was 88.9%, which was significantly higher than that in control group (57.1% The difference was statistically significant (P <0.05). The incidence of adverse reactions in the study group was lower than that in the control group, the difference was statistically significant (P <0.05). Conclusion Treatment of advanced gastric cancer with getiao capsule combined with oxaliplatin has good short-term effect, with mild adverse reactions and high safety, which deserves further study and promotion.