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过氧化物酶体增殖物激活受体(PPARs)家族是影响脂肪细胞分化和脂质代谢的主要核内转录受体,根据其结构及功能可将PPARs分为PPARα、PPARβ(亦称PPARδ)及PPARγ3种亚型。其家族成员PPARγ是目前所知唯一在脂肪组织中高水平表达的转录因子,对脂肪细胞的分化有重要调节作用。而运
Peroxisome proliferator-activated receptor (PPARs) family is a major nuclear transcriptional receptor that affects adipocyte differentiation and lipid metabolism. According to its structure and function, PPARs can be divided into PPARα, PPARβ (also known as PPARδ) and PPARγ3 kinds of subtypes. Its family member, PPARγ, is the only transcription factor known to be the only one with high level expression in adipose tissue and plays an important regulatory role in adipocyte differentiation. And transport