B流感嗜血杆菌性脑膜炎是细菌性脑膜炎的第二种常见类型,有一定的死亡率。一个3月的男婴,经脑脊液检查和细菌培养证实为B流感嗜血杆菌性脑膜炎。根据药敏试验选用氯霉素,静注及脑室注药。11天后,治疗无效果。又改用氨苄青霉素和复方增效磺胺,并行氨苄青霉素脑室注药。治疗至18天,仍无效果,病情继续发展,脑脊液白细胞高达500×10~6/L,脑室积脓,但此时培养无细菌生长。故加用利福平20mg/kg/24 B. Haemophilus influenzae meningitis is the second most common form of bacterial meningitis with some mortality. A March baby boy, confirmed by cerebrospinal fluid examination and bacterial culture as Haemophilus influenza B meningitis. Chloramphenicol according to drug sensitivity test, intravenous injection and intraventricular injection. After 11 days, the treatment had no effect. Also use ampicillin and compound synergistic sulfa, ampicillin parallel intraventricular injection. Treatment to 18 days, still no effect, the condition continues to develop, cerebrospinal fluid leukocytes as high as 500 × 10 ~ 6 / L, ventricular empyema, but at this time the cultivation of bacterial growth. So add rifampicin 20mg / kg / 24