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抗栓药物在预防缺血性卒中治疗中有重要作用。低剂量阿司匹林预防卒中与高剂量同样有效,而出血并发症明显减少。华法林与阿司匹林对预防非心栓性缺血性卒中一样有效,但其出血并发症明显增多。噻氯匹定预防卒中的效果比阿司匹林好,但伴有较严重的脑出血并发症,其预防卒中的作用并不优于阿司匹林,与后者联用预防复发性卒中并不比其单用更有效。阿司匹林与缓释双嘧达莫联用比单用阿司匹林有效,发生出血不良反应的几率仅与小剂量阿司匹林相当。
Antithrombotic drugs play an important role in the prevention of ischemic stroke. Low doses of aspirin to prevent stroke is as effective as high doses, with a significant reduction in bleeding complications. Warfarin and aspirin are as effective at preventing non-cardiac thrombotic ischemic stroke, but their bleeding complications are significantly higher. Ticlopidine is better than aspirin in preventing stroke, but with more severe complications of cerebral hemorrhage, its effect of preventing stroke is not superior to that of aspirin. Ticlopidine is no more effective than aspirin alone in preventing recurrent stroke . Aspirin and extended-release dipyridamole effective than aspirin alone, the risk of adverse reactions occurred only with low-dose aspirin.