脓毒症是感染继发的全身炎性反应综合征,重组活化蛋白C的抗凝作用对脓毒症患者已取得肯定疗效,使脓毒症导致的凝血异常受到重视。组织因子是感染诱发的主要凝血因子。该文作者就其与脓毒症的关系作一综述。 Sepsis is a systemic inflammatory response syndrome secondary to infection. The anticoagulant effect of recombinant activated protein C has achieved a positive effect on patients with sepsis, and coagulopathy caused by sepsis has been taken seriously. Tissue factor is the major coagulation factor induced by infection. The author reviews its relationship with sepsis.