论文部分内容阅读
近年来,多发性骨髓瘤(MM)的治疗取得了长足的进步。MM患者的无进展生存期(PFS)和总生存期(OS)得到了明显提高。但如何使患者获得最大程度的缓解并长期生存,乃至如何彻底治愈MM等,是亟待解决的问题。随着对骨髓瘤分子生物学性质的阐明,以及对骨髓瘤细胞内信号通路、骨髓微
In recent years, the treatment of multiple myeloma (MM) has made great strides. The progression-free survival (PFS) and overall survival (OS) of patients with MM have been significantly improved. However, how to make patients get the greatest degree of ease and long-term survival, and even how to completely cure MM, is a problem to be solved. With the elucidation of the molecular biological properties of myeloma, as well as myeloma intracellular signaling pathways, bone marrow micro