In order to explore the changes in the growth and protein contents of Spirulina and obtain a proper strain for the fixation of carbon dioxide (CO2) from flue gas,the strains isolated from the Spirulina farms and the strain 208 were cultured under different aeration conditions including no CO2,10％ CO2 and coal power plant flue gas supplements.The physiological indexes including filament length,biomass yield and chlorophyll a,soluble protein and phycocyanin contents were determined,respectively.When cultured without CO2 supplement,the strain 4-5 exhibited the highest biomass yield (1.880 gL-1) and a specific growth rate (0.367 d-1).However,the specific growth rate of all strains decreased significantly when they were cultured under 10％ CO2 and unfiltered coal power plant flue gas supplements.Considerable differences were noted in the performance of the experimental microalgal strains under different contemporaneous conditions.The strain 7-8 achieved the highest biomass yield (1.603 gL-1) and relatively high phy-cocyanin content (7.1％) under 10％ CO2 supplement.We noted that strain 4-5 had the highest specific growth rate (0.182 d-1) and biomass yield (0.43 gL-1) under coal power plant flue gas supplement.Strain 6-10 displayed the highest soluble protein content (66.02％),and strain 7-8 showed the highest phycocyanin content (9.28％) under coal power plant flue gas supplement.