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目的分析江西省近8年出生缺陷发生情况、变化趋势及相关影响因素。为卫生行政部门制定出生缺陷干预措施提供依据。方法对2000年~2007年江西省32所出生缺陷监测医院261008例围产儿进行出生缺陷监测,统计分析出生缺陷发生率,各类出生缺陷的发生率、类别、构成比和相关因素。结果8年间共监测围产儿261008例,发现出生缺陷儿3553例,发生率为136.1/万,并呈逐年升高趋势,我省高发畸形依次为先天性心脏病、多指(趾)、外耳其他畸形、总唇裂、先天性脑积水。出生缺陷发生率农村(167.4/万)高于城镇(121.7/万),男孩(149.8/万)高于女孩(116/万),产妇年龄中<20岁组发生率最高,20-30岁组最低,两组比较有统计学意义。结论做好一级预防工作,从产前-围产保健预防模式向孕前-围孕保健预防模式转变,确定重点保健人群,探索降低出生缺陷、提高出生人口素质的有效途径和方法。
Objective To analyze the incidence of birth defects in Jiangxi Province in recent 8 years, trends and related factors. Provide the basis for the health administrative departments to formulate birth defects intervention measures. Methods A total of 26 1008 perinatal infants in 32 birth defect monitoring hospitals in Jiangxi Province from 2000 to 2007 were monitored for birth defects. The incidence of birth defects, the incidence, types, constituent ratios and related factors of birth defects were statistically analyzed. Results A total of 26 1008 perinatal children were monitored during the 8 years. 3553 cases of birth defects were found, with an incidence rate of 136.1 / 000 and a trend of increasing year by year. High incidence deformities in our province were congenital heart disease, multiple fingers (toe) and other external ear Deformity, total cleft lip, congenital hydrocephalus. The incidence of birth defects was higher in rural areas (167.4 / million) than in urban areas (121.7 / million), boys (149.8 / 10 000) higher than girls (11.6 / 10 000), maternal age <20 years old was the highest, The lowest, the two groups were statistically significant. Conclusions To do a good job in primary prevention, from prenatal - perinatal care prevention model to prenatal care and perinatal care prevention model to change, to identify key health care workers to explore ways to reduce birth defects and improve the quality of birth population effective ways and methods.