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目的 :了解海洛因依赖病人乙型肝炎病毒的感染情况。方法 :比较门诊病人、普通精神病人和住院海洛因依赖病人之间 HBs Ag,抗 -HBs,抗 -HBc不同的感染程度 ,并将海洛因依赖病人的 HBs Ag,抗 -HBs,抗 -HBc及乙肝标记的阳性率与国内外的感染情况进行比较。结果 :海洛因依赖病人 HBs Ag的阳性率显著高于国内普通人群和国外海洛因依赖者 ,抗 -HBs的阳性率高于国内普通人群、门诊病人、普通精神病人和国外海洛因依赖者 ,抗 -HBc的阳性率低于国内普通人群、门诊病人和国外海洛因依赖者 ,抗 -HBc和抗 -HBs可同时存在且呈负相关关系。结论 :目前国内海洛因依赖者乙肝病毒的感染情况与普通人群、一般病人及与国外海洛因依赖者不同 ,其高抗 -HBs阳性率和相对较低的抗 -HBc阳性率以及抗 -HBc和抗 -HBs的负相关关系意义未明 ,需进一步研究
Objective: To understand the hepatitis B virus infection in heroin dependent patients. Methods: The levels of HBsAg, anti-HBs and anti-HBc infection among outpatients, general mental patients and inpatient heroin dependence patients were compared. HBsAg, anti-HBs, anti-HBc and HBV markers in heroin dependent patients The positive rate was compared with the infection status at home and abroad. Results: The positive rate of HBs Ag in heroin dependent patients was significantly higher than that in the general population and overseas heroin addicts. The positive rate of anti-HBs was higher than that in the general population, outpatients, general mental patients and overseas heroin addicts, and anti-HBc The positive rate is lower than the general population in the country, outpatients and foreign heroin dependence, anti-HBc and anti-HBs can exist at the same time and have a negative correlation. Conclusions: At present, the infection status of hepatitis B virus in domestic heroin addicts is different from the general population, general patients and foreign heroin addicts. The positive rate of anti-HBs and the relatively low positive rate of anti-HBc as well as the anti-HBc and anti- The negative correlation of HBs is not clear, and needs further study