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目的:观察中药联合康复治疗对脑梗死急性期患者同型半胱氨酸水平的疗效。方法:将患者120例随机分为4组,对照组(30例)采用口服叶酸、维生素B6、维生素B12等西医常规治疗;中药组(30例)在西医常规治疗的基础上,口服中药方中经2号方;康复组(30例)在西医常规治疗的基础上,配合康复训练;综合组(30例)在西医常规治疗的基础上,口服中药方中经2号方并配合康复训练。4组均以14 d为1个疗程,观察并比较4组治疗前后同型半胱氨酸水平(Hcy)、神经功能缺损程度评分(CNDS)及临床疗效。结果:4组治疗后Hcy、CNDS均有不同程度的改善(与本组治疗前比较,P<0.05),综合组改善优于对照组、中药组和康复组(P<0.05),综合组疗效优于对照组、中药组和康复组(P<0.05)。结论:中药联合康复能降低血中Hcy的浓度,提高脑梗塞急性期患者生活质量。
Objective: To observe the curative effect of traditional Chinese medicine combined rehabilitation on homocysteine in patients with acute cerebral infarction. Methods: One hundred and twenty patients were randomly divided into four groups. The control group (30 cases) was treated with routine western medicine such as oral folic acid, vitamin B6 and vitamin B12. The traditional Chinese medicine group (30 cases) The second group (30 cases) received rehabilitation training on the basis of routine treatment of Western medicine; the third group (30 cases) received traditional Chinese medicine prescriptions on the basis of routine treatment of Western medicine. The four groups were given a course of treatment for 14 days. The levels of homocysteine (Hcy), neurologic deficit score (CNDS) and clinical effect were observed and compared between the four groups before and after treatment. Results: The levels of Hcy and CNDS were improved to some extent in the 4 groups (P <0.05 compared with before treatment), and the improvement in the combined group was superior to that in the control group, the traditional Chinese medicine group and the rehabilitation group (P <0.05) Better than the control group, traditional Chinese medicine group and rehabilitation group (P <0.05). Conclusion: The Chinese traditional medicine combined rehabilitation can reduce the concentration of Hcy in the blood and improve the quality of life in patients with acute cerebral infarction.