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目的了解艾滋病(AIDS)抗病毒治疗(ART)失访病人的流行病学特征,为减少ART失访提供有价值的信息。方法采用回顾性分析方法,对2005年9月至2013年12月,南宁市第四人民医院进行ART的失访AIDS病人,通过建立的失访病历档案材料,收集研究对象性别、年龄、失访的时间、感染途径、地区等资料,进行统计学分析。结果 2005年9月至2013年12月,已确诊为AIDS病人并实施国家统一免费抗病毒治疗的病人共3996例,失访165例,总失访率为4.13%。30~39岁年龄段失访率占41.81%,40~49岁占23.64%。44.85%AIDS病人失访发生在抗病毒治疗的1年内。静脉吸毒共用注射器途径感染AIDS者的失访率明显高于性及其他传播途径(χ2=5.590,P<0.05);南宁市外的失访率高于南宁市市内(χ2=9.087,P<0.05)。结论针对静脉吸毒人群及南宁市外病人的高失访率、失访发生的时间早等特征,采取相应的措施,加强依从性教育,建立协调机制,可降低失访率。
Objective To understand the epidemiological characteristics of patients lost to ART in ART and to provide valuable information for reducing the number of ART lost. Methods A retrospective analysis method was used to analyze the AIDS patients lost from ART in Nanning Fourth People’s Hospital from September 2005 to December 2013. The data of the lost patients were collected to collect the gender, Time, route of infection, area and other data for statistical analysis. Results From September 2005 to December 2013, 3996 AIDS patients were diagnosed as AIDS-free patients and implemented a national free anti-virus therapy. 165 patients were lost to follow-up, with a total loss rate of 4.13%. The rate of loss to follow up was 41.81% in the age group of 30-39 years and 23.64% in the age group of 40-49 years. 44.85% of AIDS patients lost their follow-up occurred within 1 year of anti-virus treatment. The rate of lost to follow-up in intravenous drug use syringes was significantly higher than that in other sexes and other routes of transmission (χ2 = 5.590, P <0.05). The rate of non-attendance outside Nanning was higher than that in Nanning (χ2 = 9.087, P < 0.05). Conclusion For the intravenous drug users and patients outside Nanning City, the high-lost rate and early loss of follow-up were taken. Corresponding measures were taken to strengthen compliance education and establish a coordination mechanism to reduce the rate of lost follow-up.