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目的：探讨动脉血乳酸水平、APACHEII评分对脓毒症患者预后的评价应用价值。方法随机选取该院2013年4月-2014年6月收治的脓毒血症患者共60例，将60例患者按预后分为生存组和死亡组，分别测定两组患者入院治疗后12 h、24 h、48 h、72 h各时点的动脉血乳酸指标、APACHEII评分情况。结果生存组治疗后12 h、24 h、48 h、72 h动脉血乳酸水平和APACHEII评分，均优于同期死亡组，差异有统计学意义(P<0.05)。结论动脉血乳酸水平及APACHEII评分可以反应脓毒血症预后效果，对两项指标的综合运用对疗效评估十分有效。“,”Objective To investigate evaluation value of the arterial blood lactate levels, APACHEII score on prognosis in patients with sepsis. Methods From April 2013 to June 2014 selected 60 sepsis patients admitted to our hospital, and according to the prognosis divided them into survival group and death group. Two groups of patients were measured after hospitalized 12 h, 24 h, 48 h, 72 h arterial blood lactate index each time point, APACHEII score situation. Results After treatment 12 h, 24 h, 48 h, 72 h arterial blood lactate level and APACHEII scores of the survival group were better than the same period of the death group (P<0.05). Conclusion The arterial blood lactate levels and APACHEII score can react sepsis prognosis and the integrated use of two indica tors is very effective to assess the treatment efficacy.