垂体催乳素腺瘤是最常见的功能性垂体腺瘤,可致高催乳素血症。治疗药物主要有溴隐亭、卡麦角林和喹高利特。溴隐亭为国内市场唯一用于治疗垂体催乳素腺瘤的药物,并被美国FDA批准用于治疗2型糖尿病。卡麦角林1997年被美国FDA批准上市,用于治疗高催乳素血症及帕金森病。喹高利特于1996年在瑞士批准上市,目前已在欧洲广泛使用。本文从药动学特点、用法用量、作用特点、不良反应等方面综述上述3种药物的特点。 Pituitary prolactin adenoma is the most common functional pituitary adenoma, can cause hyperprolactinemia. The main therapeutic drugs are bromocriptine, cabergoline and quinagalit. Bromocriptine is the only drug used to treat pituitary prolactinomas in the domestic market and is approved by the U.S. FDA for the treatment of type 2 diabetes. Cabernet Sauvignon was approved by the US FDA in 1997 for the treatment of hyperprolactinemia and Parkinson’s disease. Quinoligrate was approved in Switzerland in 1996 and is now widely used in Europe. This article summarizes the characteristics of above three kinds of drugs from the aspects of pharmacokinetics, usage dosage, action characteristics and adverse reactions.