血清氟水平是评价人群氟负荷的重要指标,在评价机体受氟危害及氟中毒中具有较为重要的意义〔1〕。但由于血清氟含量低,受采集时间、采集和分析过程的影响,因此到目前为止,尚没有世界卫生组织或各国科研机构所公认的血清氟或血浆氟的含量标准〔2-3〕。基准剂量指一个使某种反应增加到某一个特定水平时的剂量,该特定水平下的反应就是基准剂量反应,由于该反应是实验可检出的反应范围的下限,从数 Serum fluorine level is to assess the population of fluoride an important indicator of the body in assessing the body by fluorine and fluoride poisoning has a more important significance (1). However, due to the low serum fluorine content, the time of collection, the process of collection and analysis, so far, there is no WHO or national scientific research institutions recognized serum fluoride or plasma fluoride content [2-3]. Reference dose refers to a certain reaction to increase a certain level of the dose, the specific level of the reaction is the reference dose response, the reaction is experimentally detectable lower limit of the reaction range, from the number