论文部分内容阅读
采用Gomori钙-钴染色法对80例非造血系统恶性肿瘤外周血中性粒细胞碱性磷酸酶(NAP)活力进行了观察,发现其阳性率及阳性指数(积分)明显降低,分别为15.76±13.85％,18.19±16.93分,与59例健康人33.78±8.7％,54.51±15.75分及60例良性肿瘤患者34.57±16.92％,53.60±21.83分析比较差异非常显著(P<0.01)。而良性肿瘤患者与健康人NAP的阳性率及积分比较无差异(P>0.05)。同时对18例宫颈癌患者与42例子宫肌瘤患者的NAP活力进行了比较,其阳性率和阳性指数分别为18.00±14.19％,22.28±18.12分和39.47±19.05％,47.14±31.15分,差异亦非常显著(P<0.01)。提示NAP活力测定可作为对非造血系统恶性肿瘤筛选诊断时一种简便易行、经济实用的方法。
The Gomori calcium-cobalt staining method was used to observe the neutrophil alkaline phosphatase (NAP) activity in peripheral blood of 80 non-hematopoietic malignancies. It was found that the positive rate and positive index (integral) were significantly reduced, which was 15.76±. 13.85%, 18.19±16.93 points were significantly different from 59 healthy subjects (33.78±8.7%, 54.51±15.75 points) and 60 benign tumor patients (34.57±16.92%, 53.60±21.83) (P<0.01). However, there was no difference in the positive rates and scores of NAP between benign tumor patients and healthy individuals (P>0.05). At the same time, the NAP activities of 18 patients with cervical cancer and 42 patients with uterine fibroids were compared. The positive rate and positive index were 18.00±14.19%, 22.28±18.12 and 39.47±19.05%, 47.14±31.15, respectively. Also very significant (P<0.01). It is suggested that the NAP activity assay can be used as a simple, economical and practical method for screening and diagnosis of non-hematopoietic malignancies.