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目的探讨肿瘤特异性生长因子(TSGF)在肺癌患者中检测的诊断价值。方法采用TSGF检测试剂对360例确诊肺癌患者、170例肺部良性病患者和30例正常人的血清进行TSGF检测分析。结果360例肺癌患者,检出恶性TSGF,阳性315例,占87.5%;170例肺部良性疾病,阳性24例,占14.1%;30例正常人,阳性0例。其中,肺癌组与各组相比较,差异具有统计学意义。肺癌组的TSGF阳性率明显高于其他各组(P<0.01)。结论检测血清TSGF可辅助肺癌的诊断,在正常人体检筛查肺癌中具有一定的价值。
Objective To investigate the diagnostic value of tumor specific growth factor (TSGF) in lung cancer patients. Methods Serum TSGF was detected in serum of 360 patients diagnosed with lung cancer, 170 patients with benign lung disease and 30 normal persons by using TSGF reagent. Results Among 360 lung cancer patients, malignant TSGF was detected in 315 cases (87.5%), 170 cases of pulmonary benign disease were positive in 24 cases (14.1%), 30 cases were normal and 0 cases were positive. Among them, lung cancer group compared with each group, the difference was statistically significant. The positive rate of TSGF in lung cancer group was significantly higher than that in other groups (P <0.01). Conclusion Detection of serum TSGF can assist in the diagnosis of lung cancer, screening of lung cancer in normal people has a certain value.