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目的了解巨块与非巨块宫颈癌在宫颈浸润的深度、淋巴转移、复发率及生存率等差异。方法对 5 7例巨块型 (宫颈肿瘤≥ 4cm )与6 4例非巨块型 (宫颈肿瘤 <4cm )宫颈癌进行回顾性对照分析。结果宫颈深层浸润巨块组 75 .4% ,非巨块组 2 6 .6 % ( P<0 .0 1)。盆腔淋巴转移率巨块组 2 8.0 % ,非巨块组 14.1% ( P<0 .0 5 )。宫颈肿瘤组织放疗反应 度巨块组 6 6 .7% ,非巨块组 2 6 .6 % ( P<0 .0 1)。 3年内复发率巨块组 47.4% ,非巨块组 2 1.9% ( P<0 .0 1)。 5年生存率巨块组 5 9.7% ,非巨块组 85 .9% ( P<0 .0 1)。结论巨块型宫颈癌宫颈浸润深度、淋巴转移率及肿瘤对放疗的抗拒性均比非巨块型增加 ,而复发率比非巨块型高 ,生存率比其低 ,因此应提倡综合治疗
Objective To understand the difference of depth of cervical infiltration, lymph node metastasis, recurrence rate and survival rate between giant and non-giant cervical cancer. Methods Retrospective and comparative analysis was performed on 57 cases of massive (≥ 4 cm) cervical cancer and 64 cases of non-massive (≤ 4 cm) cervical cancer. Results Cervical deep infiltration of giant block group 75.4%, non-giant block group 26.6% (P <0.01). Pelvic lymph node metastasis rate was 8.0% in the macroblock group and 14.1% in the non-macroblock group (P <0.05). Cervical tumor tissue radiotherapy response was 64.7% in the macroblock group and 26.6% in the non-macroblock group (P <0.01). The recurrence rate in 3 years was 47.4% in the macroblock group and 1.9% in the non-macroblock group (P <0.01). The 5-year survival rate was 59.7% for the macroblock group and 85.9% for the non-macroblock group (P <0.01). CONCLUSION: The depth of cervical invasion, lymphatic metastasis rate and tumor resistance to radiotherapy in giant-type cervical cancer are all higher than those in non-giant type, but the recurrence rate is higher than non-giant type and the survival rate is lower than that