1例57岁女性患者,因右肺小细胞肺癌行第2次化疗。化疗前给予格拉司琼止吐、苯海拉明抗过敏。然后静脉滴注替尼泊苷注射液100mg+5%葡萄糖注射液250ml,60滴/min。用药约2min后,患者突然出现憋气、紫绀,随即意识丧失,呼吸、心跳停止。立即停药,给予心肺复苏、升压及抗过敏治疗。10min后患者呼吸、心跳恢复,HR150～160次/min,BP100/60mmHg,全身出现大面积红色皮疹。继续给予抗过敏、抗休克等治疗。12h后皮疹消退,17h后患者清醒,一般状况好转。 A 57-year-old female patient underwent second chemotherapy for right lung small cell lung cancer. Pretreatment given granisetron antiemetic, diphenhydramine anti-allergy. Then intravenous infusion of teniposide 100mg + 5% glucose injection 250ml, 60 drops / min. About 2min after treatment, the patient suddenly suffocated, cyanosis, then loss of consciousness, breathing, cardiac arrest. Immediate withdrawal, cardiopulmonary resuscitation, boost and anti-allergy treatment. After 10min, the patient resumed breathing and recovered his heartbeat. HR150 ~ 160 times / min, BP100 / 60mmHg, a large red rash appeared in the whole body. Continue to give anti-allergy, anti-shock and other treatment. After 12h, the rash subsided and the patient was awake after 17h. The general condition improved.