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一项50家不同研究中心参与的全球研究发现了数百个导致5种常见、难治炎性疾病的基因,为开发这些疾病的新疗法铺平了道路。这项研究由澳大利亚昆士兰科技大学(QUT)和德国基尔大学(Christian-Albrechts-University)领导,最新发表于国际期刊《Nature Genetics》。该研究共同资深作者、QUT健康和生物医学创新研究所教授Matthew Brown说,他们研究了强直性脊柱炎、克罗恩病和溃疡性结肠炎(统称为炎性肠病)、牛皮癣和原发性硬化性胆管炎。“这些疾病影响大约3%的世界人口,通常一同发生于家族和个人中。最大的问题是,这是否是由共
A global study involving 50 different research centers uncovered hundreds of genes that led to five common, refractory inflammatory diseases, paving the way for new therapies to develop these diseases. The study, led by the Queensland University of Technology (QUT) in Australia and Christian-Albrechts-University in Germany, was recently published in the international journal Nature Genetics. Matthew Brown, a co-senior author and professor at the QUT Institute for Health and Biomedical Innovation, said that they studied ankylosing spondylitis, Crohn’s disease and ulcerative colitis (collectively referred to as inflammatory bowel disease), psoriasis and primary Sclerosing cholangitis. ”The world population, which affects about 3% of these diseases, usually occurs in families and individuals alike. The big question is whether this is a total