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139注射液成份为油酸包封在含有大豆磷酯、胆固醇、非离子表面活性剂和聚维酮(聚烯吡酮)等组成的脂质体中。常见寒战、发热等不良反应,但过敏性休克报道尚未查到。今报道1例如下,希临床同道引起注意。患者谷某,男性,65yr,已婚。主因贲门癌术后1年余入院做第5次辅助化疗。前5次化疗方案为丝裂霉素、5-氟尿嘧啶、阿糖胞苷联合化疗。本次单用油酸多相脂质体注射液-139(简称:139注射液)。查体:T36.4℃;P74次/min;BP14.7/93kPa(110/70mmHg)。血、尿、便三大常规及
139 Injection is oleic acid encapsulated in liposomes containing soy phosphates, cholesterol, non-ionic surfactants and povidone (povidone). Common chills, fever and other adverse reactions, but no reports of anaphylactic shock has been found. 1 case reported today, Xi clinical colleagues attract attention. Patient Gumou, male, 65yr, married. Mainly because of cardiac surgery more than 1 year after admission to do the fifth adjuvant chemotherapy. The first 5 chemotherapy regimens were mitomycin, 5-fluorouracil and cytarabine in combination with chemotherapy. The single oleaginous phase liposome injection-139 (referred to: 139 injection). Examination: T36.4 ℃; P74 times / min; BP14.7 / 93kPa (110/70 mmHg). Blood, urine, then the three major conventions