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术前放疗:美国Oregeon省保健科学中心大学对97例直肠乙状结肠癌进行了高剂量术前照射(5000~6000rad)。放疗后4~7周外科切除。其中57例可切除病例中40例做了根治性切除,5年无病生存者21例(53%),较过去仅行外科切除5年生存率38%有明显的提高。术前行2000~2500rad放疗完全切除者盆腔复发率为29%,而单纯外科切除盆腔复发率为37%。经过术前照射切除的标本仅有28.7%发现有阳性淋巴结,而仅行手术的则是41.2%。
Preoperative radiotherapy: The University of Oregon Health Science Center in the United States performed high-dose preoperative irradiation (from 5,000 to 6,000 rad) on 97 cases of rectal sigmoid colon cancer. Surgical resection 4 to 7 weeks after radiotherapy. Among the 57 resectable cases, radical resection was performed in 40 cases, and 21 cases (53%) were disease-free survivors in 5 years, which was significantly higher than the previous 5-year survival rate of surgical resection of only 38%. The recurrence rate of pelvic resection in patients who underwent complete resection of radiation from 2000 to 2500 rad before surgery was 29%, while the recurrence rate after simple surgical resection of the pelvis was 37%. Only 28.7% of specimens resected before surgery were found to have positive lymph nodes, compared with 41.2% of those who underwent surgery alone.