【摘 要】
：
D,L-lactide was prepared from D,L-lactic acid by means of polymerization and depolymerization at low vacuum level.Morpholine-2,5-dione (MD) was synthesized from
【机 构】
：
School of Materials Science and Engineering,Institute of Polymer Material Engineering
【基金项目】
：
the Science Foundation of Jiaxing Science and Technology Bureau,China;the Natural Science Foundation of Zhejiang Province,China;国家自然科学基金;the Science and Technology Department of Zhejiang Province,Chin
论文部分内容阅读
D,L-lactide was prepared from D,L-lactic acid by means of polymerization and depolymerization at low vacuum level.Morpholine-2,5-dione (MD) was synthesized from the cyclization of chloroacetyl glycine which was made from chloroacetyl chloride and glycine in the basic condition.A novel copolymer (PLAMD) with D,L-lactide (D,L-LA) and morpholine-2,5-dione (MD) was synthesized using stannous octoate as initiator,and characterized with FT-IR and 1HNMR.The biocompatibility of PLAMD and PLA was investigated by MTT and microscope.The results show that amino acid is introduced into PDLLA marn chain.PLAMD has better cell affinity than PLA,so it is a promising biomaterial.
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