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肝硬化顽固性腹水,虽经限制钠盐饮食和利尿剂治疗,效果往往不理想。此种病人因长期大量利尿,极易导致电解质紊乱,有效血容量减少,肾脏灌注减少致功能性肾功衰竭。这种情况下再用利尿剂治疗亦无效。门腔部静脉吻合术虽是一种治疗措施,但对某些较重的病人或因其它原因不能耐受手术者,门腔静脉吻合术又非其适应症。因此需要寻找更为安全有效的治疗措施。近十几年来对这种顽固性腹水病人的治疗有了一些新的进展。腹水回输术是应用较多疗效较好的方法。腹水回输的基本原理是将腹水抽出;直接静脉回输或经浓缩后静脉输入以消除腹水。腹水回输入体循环,增加有效循环量,改善了肾血流量。另外腹水回输使血浆蛋白和胶体渗透压增高亦有助于利尿以达治疗目的。其方法有
Cirrhosis and refractory ascites, although limited by the sodium diet and diuretics, the effect is often not ideal. Such patients due to long-term massive diuresis, can easily lead to electrolyte imbalance, effective hypovolemia, renal perfusion reduce functional renal failure. In this case re-diuretic treatment is also invalid. Portal venous anastomosis is a treatment, but for some of the heavier patients or for other reasons can not tolerate surgery, portal venous anastomosis is not its indications. Therefore, we need to find more safe and effective treatment. In the past ten years, some new advances have been made in the treatment of such refractory ascites patients. Ascites transfusion is a more effective method to apply more. Ascites back to the basic principle of ascites drawn out; direct venous return or intravenous input to eliminate ascites after concentration. Ascites back into the body circulation, increase the effective circulation, improve renal blood flow. In addition to transfusion of ascites plasma protein and colloid osmotic increased also helps diuretic for therapeutic purposes. The method is