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免疫治疗胶质瘤是最有希望的治疗手段之一,但临床研究却未取得预期疗效。本文综述了胶质瘤组织、血循环中免疫活性细胞功能异常、胶质瘤细胞表达人类白细胞抗原和分泌细胞因子及胶质瘤相关抗原等研究进展,希望为发展胶质瘤的免疫治疗提供新的思路。
Immunotherapy glioma is one of the most promising treatment, but clinical studies have not achieved the desired effect. This review summarizes the progress of glioma tissue, the abnormal function of immunocompetent cells in the blood circulation, the expression of human leukocyte antigen and secreting cytokines and glioma-associated antigens in glioma cells, and so on. It is hoped to provide a new method for the development of glioma immunotherapy Ideas.