论文部分内容阅读
目的探讨特发性炎症性肌病患者心率与心包积液的关系。方法回顾性纳入146例特发性炎症性肌病患者,用超声心动图和胸部CT判断是否存在心包积液,运用多因素分析评估心率与心包积液的关系。结果特发性炎症性肌病中有各类心包疾病为13.69%,85%为心包积液;与无心包疾病的患者比较,有心包疾病的患者心率明显增快(P=0.006),且心包积液患者心率较心包增厚心率高;二分类Logistic回归显示心率与特发性炎症性肌病合并心包疾病相关(P=0.042,OR=1.036,95%CI:1.001~1.073),多发性肌炎本身以及罹患间质性肺病也与心包疾病相关(P<0.05)。结论心包疾病在特发性炎症性肌病中并不少见,多为心包积液,与患者心率、多发性肌炎本身以及同时罹患间质性肺病相关。
Objective To investigate the relationship between heart rate and pericardial effusion in patients with idiopathic inflammatory myopathies. Methods Retrospectively enrolled 146 patients with idiopathic inflammatory myopathies. Echocardiography and chest CT were used to determine the presence or absence of pericardial effusion. Multivariate analysis was used to evaluate the relationship between heart rate and pericardial effusion. Results In idiopathic inflammatory myopathies, there were 13.69% of all pericardial diseases and 85% of them were pericardial effusion. Compared with those without pericardial disease, heart rate of patients with pericardial disease was significantly increased (P = 0.006) Logistic regression analysis showed that heart rate was associated with idiopathic inflammatory myopathies complicated with pericardial disease (P = 0.042, OR = 1.036, 95% CI: 1.001 ~ 1.073), multiple myofibers Inflammation itself and interstitial lung disease were also associated with pericardial disease (P <0.05). Conclusions Pericardial disease is not uncommon in idiopathic inflammatory myopathies, mostly pericardial effusions, and is associated with heart rate, polymyositis, and concurrent interstitial lung disease.